AIDS Being one of the most fatal viruses in the nation, AIDS (Acquired Immunodeficiency Syndrome) is now a serious public health concern in most major U.

S. cities and in countries worldwide. Since 1986 there have been impressive advances in understanding of the AIDS virus, its mechanisms, and its routes of transmission. Even though researchers have put in countless hours, and millions of dollars it has not led to a drug that can cure infection with the virus or to a vaccine that can prevent it.

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With AIDS being the leading cause of death among adults, individuals are now taking more precautions with sexual intercourse, and medical facilities are screening blood more thoroughly. Even though HIV ( Human Immunodeficieny Virus) can be transmitted through sharing of non sterilize needles and syringes, sexual intercourse, blood transfusion, and through most bodily fluids, it is not transmitted through casual contact or by biting or blood sucking insects.Development of the AIDS Epidemic The first case of AIDS were reported in 1982, epidemiologists at the Center of Disease Control immediately began tracking the disease back wards in time as well as forward. They determined that the first cases of AIDS in the United States probably occurred in 1977. By early 1982, 15 states, the District of Columbia, and 2 foreign countries had reports of AIDS cases, however the total remained low: 158 men and 1 woman. Surprising enough more then 90 percent of the men were homosexual or bisexual. Knowing this more then 70 percent of AIDS victims are homosexual or bisexual men, and less then 5 percent are heterosexual adults. Amazing enough by December of 1983 there were 3,000 cases of AIDS that had been reported in adults from 42 states, the District of Columbia, and Puerto Rico, and the disease had been recognized in 20 other countries.

Recognizing the Extent of Infection The health of the general homosexual populations in the area with the largest number of cases of the new disease was getting looked at a lot closer by researchers. For many years physicians knew that homosexual men who reported large numbers of sexual partners had more episodes of venereal diseases and were at higher risk of hepatitis B virus infection than the rest of the population, but conicidentally with the appearance of AIDS,. other debilitating problems began to do appear more frequently. The most common was swollen glands, often accompanied by extreme fatigue, weight loss, fever, chronic diarrhea, decreased levels of blood platelets and fungal infections in the mouth. This condition was labeled ARC (AIDS Related complex).The isolation of HIV in 1983 and 1984 and the development of techniques to produce large quantities of the virus [paved the way for a battery of tests to determined the relationship between AIDS and ARC and the magnitude of the carrier problem. Using several different laboratory tests, scientists looked for antibodies against the HIV in the blood of AIDS and ARC patients.

They found that almost 100 percent of those with AIDS or ARC had the antibodies-they were seriopostive. In contrast less then one percent of persons with no known risk factors were seropositive. Definition of AIDS AIDS is defined as a disease, at least moderately predictive of defects in cell- meditated immunity, occurring in a person with no known cause for diminished resistance to that disease.Such diseases include Kaposi’s Sarcoma, Pneumocystis carnii pneumonia, and serious other opportunistic infections. After the discovery of HIV and the development of HIV-antibody test, the case definition of AIDS was updated to reflect the role of the virus in causing AIDS, but the scope of the definition remained almost the same. Transmission HIV is primarily a sexually transmitted disease, it is transmitted by both homosexual and bisexual and heterosexual activity. The first recognized case was among homosexual and bisexual men.

Many numbers of studies have shown that men who have sexual partners and those who practice receptive anal intercourse are more likely to be infected with HIV than other homosexual men.Researchers found a strong connection between HIV infection and rectal trauma, enemas before sex, and physical signs of disruption of the tissue lining the rectum. Homosexual women tend to have a very low incidence of venereal disease in general, an AIDS is no exception. Female-to-female transmission is highly uncommon, however it has been reported in one case and suggested in another.

In the reported case, traumatic sex practices apparently resulted in transmission of HIV from a woman who had acquired the virus through IV drug abuse to her non-drug- using sexual partner. 1983 was when the first heterosexual (Male to female; female to male) transmission was reported.In 1985, 1.7 percent of the adult cases of AIDS reported to the CDC (Center for Disease Control) were acquired through heterosexual activity; projections suggest that by 1991 the proportion will rise to 5 percent. Heterosexual contact is the only transmission category in which women outnumber men with AIDS. Heterosexual contacts accounts for 29 percent of AIDS cases among women in the United States, but for only 2 percent of cases among men.

Estimates of the risk of HIV transmission in unprotected intercourse with a person known to be infected with HIV are 1 in 500 for a single sexual encounter and 2 in 3 for 500 sexual encounters. The use of a condom reduces these odds to 1 in 5,000 for a single encounter and to 1 in 11 for 500 encounters. Routes NOT Involved in Transmission of HIV A study of more than 400 family members of adult and pediatric AIDS patients demonstrate that the virus is not transmitted by any daily activity related to living with or caring for an AIDS patient. Basically meaning that personal interactions typical in family relationships, such as kissing on the cheek, kissing on the lips, and hugging, have not resulted in transmission of the virus. Patterns There are three different geographic patterns of AIDS transmission. The first one is characteristic of industrializing nations with large numbers of reported AIDS cases, such as the United States, Canada, countries in Western Europe, Australia, New Zealand, and parts of Latin America.In these areas most AIDS cases have been attributed to homosexual or bisexual activity and intravenous drug abuse.

The second pattern is seen in areas of central, eastern, and southern Africa and in some Caribbean countries. Unlike pattern one most AIDS cases in these areas occur among heterosexuals, and the male-to-female ratio approaches 1 to 1. The third pattern of transmission occurs in regions of Eastern Europe, the Middle East, Asia, and most of the Pacific. It is believed that HIV was introduced to these areas in the early to mid-1980s.Any study associated with AIDS must begin with the understanding that AIDS is only one outcome of infection with HIV-1. People infected with the virus may be completely asymptomtic; they may have mildly debiliating symptoms; or they may have life-threatening conditions caused by progressive destruction of the immune system, the brain, or both.

One of the first signs of HIV-1 infection in some patients is an acute fluelike disease. The condition lasts f …